- Introduction
- History
- Natural Drug Leads
- Combinatorial Approach
- Discoveries
- Conclusion
- References
- Contact Us
Notable Recent Discoveries
The AIDS pandemic in the 1980s caused companies to research into ways to fight it. This led to the discovery of calanolides and prostration (Applied Chem). Systematic Investigation really took off in the 1970s due to an improvement in technology. This led to quite a few drug discoveries. One such example is of bryostatin1 which was isolated from the bryozoan. It is an chemotherapeutic agent that has quite a bit of use for anti-cancer agents (Applied Chem).
The antimalarial agent Arteether was developed in 2000 from the Artemisia annua, a species of wormwood traditionally used in Chinese medicine to alleviate chills and fever (aapsj). Apomorphine hydrochloride was isolated from the poppy plant in 2004. This short acting dopamine receptor antagonist is used to manage motor symptoms of Parkinson's disease (aapsj). Protopanaxadiol, a drug derived from ginseng, is currently undergoing clinical trials for its effectiveness in inducing programmed cell death in cancer cells. It has also been shown to demonstrate cytotoxicity in multi-drug resistant tumors (aapsj).
The antimalarial agent Arteether was developed in 2000 from the Artemisia annua, a species of wormwood traditionally used in Chinese medicine to alleviate chills and fever (aapsj). Apomorphine hydrochloride was isolated from the poppy plant in 2004. This short acting dopamine receptor antagonist is used to manage motor symptoms of Parkinson's disease (aapsj). Protopanaxadiol, a drug derived from ginseng, is currently undergoing clinical trials for its effectiveness in inducing programmed cell death in cancer cells. It has also been shown to demonstrate cytotoxicity in multi-drug resistant tumors (aapsj).